IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the
medication is safe, appropriate, or effective for you. Consult your healthcare professional before using
Estradiol.
ESTROGENS - ORAL (ESS-trow-jens,
conjugated)
COMMON BRAND NAME(S): Cenestin, Estinyl, Estrace, Menest, Ogen,
Premarin, Tace
What is
Estradiol
Estradiol is a hormone
and is given to women who no longer produce the proper amount.
Estradiol is
used to reduce menopause symptoms (e.g., hot flashes), for brittle
bones (osteoporosis), and treats certain cancers in both men and
women.
How to Take Estradiol
Estradiol may be taken with food or
immediately after a meal to prevent stomach upset. Take Estradiol as prescribed. Follow the dosing schedule carefully. Be
sure to ask your doctor if you have any questions.
Estradiol Warning
Estradiol has been reported
to increase the chance of womb (endometrial) cancer in women who have
been through menopause. This risk appears to depend on the length of
time Estradiol is used and the amount of estrogen per dose. If you use
Estradiol for an extended period, you should be evaluated at least
every 6 months. If you experience abnormal vaginal bleeding, notify
your doctor promptly. Estradiol is not effective in preventing
or treating a tendency toward miscarriages (natural habitual abortion)
nor the threat of miscarriage. Estradiol must not be used during
pregnancy because its use may result in birth defects or cancer later
in the child's life. If you become pregnant or think you may be
pregnant, consult your doctor immediately to discuss the risk to the fetus.
Estradiol Side Effects
May cause dizziness,
lightheadedness, headache, stomach upset, bloating, or nausea. These
effects should disappear as your body adjusts to the medication.
Notify your doctor if you experience: severe depression, calf pain,
sudden severe headache, chest pain, shortness of breath, lumps in the
breast, weakness or tingling in the arms or legs, yellowing of the
eyes or skin, changes in vaginal bleeding (spotting, breakthrough
bleeding, prolonged or complete stoppage of bleeding), stomach pain,
skin rash. If you notice other effects not listed above, contact your
doctor or pharmacist.
Estradiol Precautions
Before you take
Estradiol, tell your doctor your entire medical history, including:
family medical history (especially breast lumps and cancer), high
blood pressure, diabetes, asthma, epilepsy (seizures), migraine
headaches, liver disease, heart disease, kidney disease, depression, toxemia (high blood pressure during pregnancy), jaundice (yellowing
skin/eyes) during pregnancy, excessive weight gain and fluid retention
(bloating) during menstrual cycle, uterine fibroid tumor, abnormal
vaginal bleeding, blood clots or stroke, cholesterol or lipid
problems, gallbladder disease. Before having surgery, tell the doctor
that you take Estradiol. Depending on strength, Estradiol may cause a
patchy, darkening of the skin on the face (melasma). Higher strengths
are more likely to cause melasma. Sunlight may intensify this
darkening and you may need to avoid prolonged sun exposure and
sunlamps. Consult your doctor regarding use of sunscreens and
protective clothing. Cigarette smoking can increase the chance of
blood-clots while taking Estradiol (especially in women past the
age of 35). Estradiol should not be used during pregnancy. If you
become pregnant or think you may be pregnant, inform your doctor
immediately. Estradiol may be excreted into breast milk and its use is
not recommended while breast-feeding. Consult your doctor before
breast-feeding.
Estradiol Substance Interactions
Tell your doctor of all
and non medications you may use, especially of: hydantoins (e.g., phenytoin), barbiturates (e.g., phenobarbital),
corticosteroids (e.g., prednisone). This product can affect the
results of certain lab tests. Make sure laboratory personnel and your
doctors know you use Estradiol. Do not start or stop any medicine
without doctor or pharmacist approval.
Estradiol Overdose
If overdose is suspected,
contact your local poison control center or emergency room
immediately. Symptoms of overdose may include nausea/vomiting or
stoppage of periods.
Estradiol Notes
Do not share
Estradiol
with others.
Estradiol Missed Dose
If you miss a dose, take as
soon as remembered; do not take if it is almost time for the next
dose, instead, skip the missed dose and resume your usual dosing
schedule. Do not "double-up" the dose to catch up.
Estradiol Storage
Store Estradiol at room temperature
between 59 and 86 degrees F (between 15 and 30 degrees C) away from
moisture and sunlight. Do not store in the bathroom.
Popular Misspellings - eestradiol,
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etradiol,
etsradiol, setradiol,
stradiol