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IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of Bupropion HCL is safe, appropriate, or effective for you. Consult your healthcare professional before using Bupropion HCL.

Bupropion HCL DESCRIPTION: Bupropion - ORAL (byou-PRO-pee-on)

COMMON Bupropion HCL BRAND NAME(S): Wellbutrin

What is Bupropion HCL

Bupropion HCL is a medication used to treat depression.

How to Use Bupropion HCL

Take Bupropion HCL with food if stomach upset occurs. Take doses at regularly scheduled times each day. Do not take more or less medication than prescribed and follow your doctor's instructions carefully. Do not stop taking Bupropion HCL without notifying your doctor. Since Bupropion HCL may cause sleeplessness at first, it is best not to take this near bedtime. It may take 4 weeks or more before the full effects of Bupropion HCL are noticed.

Bupropion HCL Side Effects

Bupropion HCL is generally well tolerated. Dry mouth, headache, increased sweating, nausea/vomiting, constipation, anxiety, fatigue and blurred vision may occur. If these effects persist or worsen, notify your doctor. Report: unusual weight loss or gain, palpitations, agitation, trouble sleeping. Unlikely but report promptly: tremor, dizziness, fainting, mood changes, slowed movements, difficulty urinating, decreased sex drive, drowsiness. Very unlikely but report promptly: seizures, mental problems, fever, muscle aches, yellowing of the eyes or skin. Notify your doctor immediately if an allergic reaction to Bupropion HCL occurs. Symptoms include: difficulty breathing, rash, itching. If you notice other effects not listed above, contact your doctor or pharmacist.

Bupropion HCL Precautions

Before taking Bupropion, tell your doctor if you have: history of seizures or head injury or brain tumor, heart disease, liver or kidney disease, eating disorder, diabetes, any allergies(including medication allergies), an intention to quit smoking. Because of the possibility Bupropion HCL will make you dizzy and affect coordination, do not drive or operate machinery until you get used to Bupropion HCL's effects. Limit or avoid consumption of alcoholic beverages; alcohol can increase your risk of seizures. Chronic alcohol users who suddenly stop the intake of alcohol while taking Bupropion may increase the risk of having seizures. Suddenly stopping certain tranquilizers (e.g., diazepam, chlordiazepoxide) is not recommended because doing so may increase the risk of having seizures. Elderly patients may be more sensitive to the effects of Bupropion HCL. Tell your doctor if you are pregnant or plan to become pregnant before taking Bupropion HCL. Bupropion HCL is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using Bupropion HCL is not recommended. Consult your doctor before breast-feeding.

Bupropion HCL Medication Interactions

Before taking Bupropion tell your doctor of all nonprescription and prescription medications you may use especially: MAO inhibitors (e.g., isocarboxazid, phenelzine, tranylcypromine, pargyline, selegiline, linezolid, furazolidone); levodopa; theophylline; corticosteroids (e.g. prednisone); seizure medications; sedatives; ritonavir; tranquilizers/psychiatric medications (e.g., chlorpromazine); other antidepressants (e.g., amitriptyline); salicylates (e.g., aspirin, salsalate); isoniazid; chlolinesterase inhibitors (e.g., tacrine, donepezil); morphine; adrenaline-like medications (e.g., pseudoephedrine); narcotic pain medications (e.g., codeine). Excess caffeine intake can increase the chance of seizures with Bupropion HCL. Check all nonprescription/prescription medication labels for caffeine. Consult doctor or pharmacist. A certain product used to help quit smoking contains Bupropion. Do not take that product while using this one. Do not start or stop any medicine without doctor or pharmacist approval.

Bupropion HCL Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include seizures, hallucinations, rapid heart rate, and loss of consciousness.

Bupropion HCL Notes

Do not allow anyone else to take Bupropion HCL.

Bupropion HCL Missed Dose

Take any missed dose as soon as possible but not if it is within 4 hours of the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double-up" the dose.

Bupropion HCL Storage

Store at room temperature and keep away from moisture and sunlight. Do not store in the bathroom.


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